David H. Gutmann

Springer Nature publications

• Article

  Poly(I:C) suppresses NF1-associated optic pathway glioma growth through TLR3-dependent and TLR3-independent modulation of microglial ERK signaling

  • Jit Chatterjee
  • Elvedina Subasic
  • David H. Gutmann

  in Acta Neuropathologica Communications

  23 October 2026 Open Access
• Article

  Human single cell RNA-sequencing reveals a targetable CD8⁺ exhausted T cell population that maintains mouse low-grade glioma growth

  • Rasha Barakat
  • Jit Chatterjee
  • David H. Gutmann

  in Nature Communications

  28 November 2024 Open Access

  
• Article

  Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice

  • Yuan Pan
  • Jared D. Hysinger
  • Michelle Monje

  in Nature Neuroscience

  30 May 2024 Open Access

  
• Article

  Brain injury drives optic glioma formation through neuron-glia signaling

  • Jit Chatterjee
  • Joshua P. Koleske
  • David H. Gutmann

  in Acta Neuropathologica Communications

  2 February 2024 Open Access

  
• Chapter

  Neurofibromatosis Type 1 Mouse Models

  • Jit Chatterjee
  • Joshua P. Koleske
  • David H. Gutmann

  in The RASopathies

  1 January 2024

  
• Article

  Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma

  • Zhihong Chen
  • Nishant Soni
  • Dolores Hambardzumyan

  in Nature Communications

  3 April 2023 Open Access

  
• Article

  Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling

  • Corina Anastasaki
  • Jit Chatterjee
  • David H. Gutmann

  in Acta Neuropathologica Communications

  19 August 2022 Open Access

  
• Article

  Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1

  • Corina Anastasaki
  • Juan Mo
  • David H. Gutmann

  in Nature Communications

  19 May 2022 Open Access

  
• Article

  Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia

  • Jit Chatterjee
  • Shilpa Sanapala
  • David H. Gutmann

  in Nature Communications

  8 December 2021 Open Access

  
• Article

  NF1 mutation drives neuronal activity-dependent initiation of optic glioma

  • Yuan Pan
  • Jared D. Hysinger
  • David H. Gutmann

  in Nature

  26 May 2021

  
• Article

  Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1)

  • Michael J. Fisher
  • David T. W. Jones
  • David H. Gutmann

  in Acta Neuropathologica

  14 February 2021

  
• Article

  Midkine activation of CD8⁺ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth

  • Xiaofan Guo
  • Yuan Pan
  • David H. Gutmann

  in Nature Communications

  1 May 2020 Open Access

  
• Article

  Correction to: Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

  • Verena Haage
  • Marcus Semtner
  • David H. Gutmann

  in Acta Neuropathologica Communications

  8 January 2020 Open Access

  
• Chapter

  The Sociobiology of Brain Tumors

  • David H. Gutmann

  in Tumor Microenvironment

  1 January 2020

  
• Article

  Reply to ‘Assembling the brain trust: the multidisciplinary imperative in neuro-oncology’

  • Kenneth Aldape
  • Kevin M. Brindle
  • Richard J. Gilbertson

  in Nature Reviews Clinical Oncology

  31 May 2019
• Article

  Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

  • Verena Haage
  • Marcus Semtner
  • David H. Gutmann

  in Acta Neuropathologica Communications

  14 February 2019 Open Access

  
• Article

  Challenges to curing primary brain tumours

  • Kenneth Aldape
  • Kevin M. Brindle
  • Richard J. Gilbertson

  in Nature Reviews Clinical Oncology

  7 February 2019 Open Access

  
• Article

  Variability of Betweenness Centrality and Its Effect on Identifying Essential Genes

  • Christina Durón
  • Yuan Pan
  • Ami Radunskaya

  in Bulletin of Mathematical Biology

  22 October 2018

  
• Article

  Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients

  • Mark R Woodford
  • Rebecca A Sager
  • Mehdi Mollapour

  in The EMBO Journal

  10 November 2017 Open Access

  
• Article

  Neurofibromatosis type 1

  • David H. Gutmann
  • Rosalie E. Ferner
  • Kimberly J. Johnson

  in Nature Reviews Disease Primers

  23 February 2017

  
• Article

  The role of microglia and macrophages in glioma maintenance and progression

  • Dolores Hambardzumyan
  • David H Gutmann
  • Helmut Kettenmann

  in Nature Neuroscience

  29 December 2015

  
• Article

  Associations between allergic conditions and pediatric brain tumors in Neurofibromatosis type 1

  • Bree Porcelli
  • Nancy L. Zoellner
  • Kimberly J. Johnson

  in Familial Cancer

  14 December 2015
• Article

  HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1

  • A Omrani
  • T van der Vaart
  • Y Elgersma

  in Molecular Psychiatry

  28 April 2015

  
• Article

  The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα_12/13 and RhoA

  • Sarah D. Ackerman
  • Cynthia Garcia
  • Kelly R. Monk

  in Nature Communications

  21 January 2015

  
• Article

  Parental age and Neurofibromatosis Type 1: a report from the NF1 Patient Registry Initiative

  • Qian Liu
  • Nancy Zoellner
  • Kimberly J. Johnson

  in Familial Cancer

  10 December 2014

  
• Article

  Morphologic and immunohistochemical features of malignant peripheral nerve sheath tumors and cellular schwannomas

  • Melike Pekmezci
  • David E Reuss
  • Arie Perry

  in Modern Pathology

  5 September 2014

  
• Article

  Neurofibromatosis type 1 and chronic neurological conditions in the United States: an administrative claims analysis

  • Chinwe C. Madubata
  • Margaret A. Olsen
  • Kimberly J. Johnson

  in Genetics in Medicine

  5 June 2014
• Article

  Advances in the treatment of neurofibromatosis-associated tumours

  • Andrew L. Lin
  • David H. Gutmann

  in Nature Reviews Clinical Oncology

  13 August 2013

  
• Article

  Erratum to: Optic nerve tortuosity in children with neurofibromatosis type 1

  • Joyce Ji
  • Joshua Shimony
  • David H. Gutmann

  in Pediatric Radiology

  10 June 2013
• Article

  Optic nerve tortuosity in children with neurofibromatosis type 1

  • Joyce Ji
  • Joshua Shimony
  • David H. Gutmann

  in Pediatric Radiology

  2 May 2013

  
• Article

  The molecular and cell biology of pediatric low-grade gliomas

  • Y-H Chen
  • D H Gutmann

  in Oncogene

  29 April 2013

  
• Article

  BRAF^V600E mutation is a negative prognosticator in pediatric ganglioglioma

  • Sonika Dahiya
  • Devon H. Haydon
  • Jeffrey R. Leonard

  in Acta Neuropathologica

  23 April 2013

  
• Article

  Merlin isoform 2 in neurofibromatosis type 2–associated polyneuropathy

  • Alexander Schulz
  • Stephan L Baader
  • Helen Morrison

  in Nature Neuroscience

  3 March 2013

  
• Article

  NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma

  • A C Solga
  • S M Gianino
  • D H Gutmann

  in Oncogene

  14 January 2013

  
• Article

  miRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells

  • N Kliese
  • P Gobrecht
  • C Mawrin

  in Oncogene

  29 October 2012

  
• Article

  Visual acuity in children with low grade gliomas of the visual pathway: implications for patient care and clinical research

  • Robert A. Avery
  • Rosalie E. Ferner
  • Grant T. Liu

  in Journal of Neuro-Oncology

  28 July 2012

  
• Article

  Parent-of-origin in individuals with familial neurofibromatosis type 1 and optic pathway gliomas

  • K. J. Johnson
  • M. J. Fisher
  • D. H. Gutmann

  in Familial Cancer

  25 July 2012
• Chapter

  NF1-Associated Optic Glioma

  • Anne C. Solga
  • David H. Gutmann

  in Neurofibromatosis Type 1

  1 January 2012

  
• Protocol

  Using Genetically Engineered Mouse Models to Understand Low-Grade Glioma Development and Growth in Children

  • Aparna Kaul
  • Ibrahim Hussain
  • David H. Gutmann

  in Animal Models of Brain Tumors

  1 January 2012

  
• Article

  Identification of transcriptional regulatory networks specific to pilocytic astrocytoma

  • Hrishikesh Deshmukh
  • Jinsheng Yu
  • Rakesh Nagarajan

  in BMC Medical Genomics

  11 July 2011 Open Access