Table 1 Correlation of the expression of CD44v6 and MSI2 with clinical-pathological variables in HCC patients
Clinical-Pathological Variables | Low CD44v6 (n = 43) | High CD44v6(n = 39) | P-value | Low MSI2(n = 37) | High MSI2(n = 45) | P-value |
|---|---|---|---|---|---|---|
Age(years) | ||||||
Young(≤median,48) | 27 | 20 | P = 0.293 | 22 | 25 | P = 0.722 |
Old(>median,48) | 16 | 19 | 15 | 20 | ||
AFP(ng/ml) | ||||||
Low(≤20) | 8 | 13 | P = 0.127 | 11 | 10 | P = 0.438 |
High(>20) | 35 | 26 | 26 | 35 | ||
HBsAg | ||||||
Negative | 9 | 3 | P = 0.090 | 7 | 5 | P = 0.320 |
Positive | 34 | 36 | 30 | 40 | ||
GGT(U/I) | ||||||
Low(≤50) | 10 | 17 | P = 0.050 | 10 | 17 | P = 0.303 |
High(>50) | 33 | 22 | 27 | 28 | ||
Tumor Differentiation | ||||||
Well differentiated | 10 | 7 | P = 0.554 | 13 | 4 | **P = 0.004 |
Moderately to poorly differentiated | 33 | 32 | 24 | 41 | ||
Vascular Invasion | ||||||
Absence | 34 | 34 | P = 0.330 | 30 | 38 | P = 0.687 |
Presence | 9 | 5 | 7 | 7 | ||
Tumor Size | ||||||
Small(≤5 cm) | 21 | 13 | P = 0.155 | 11 | 23 | P = 0.051 |
Large(>5 cm) | 22 | 26 | 26 | 22 | ||
Lymph Node Metastasis | ||||||
Absence | 40 | 34 | P = 0.373 | 32 | 42 | P = 0.298 |
Presence | 3 | 5 | 5 | 3 | ||
TNM stagea | ||||||
Early stage (I—II) | 21 | 10 | *P= 0.031 | 11 | 20 | P = 0.171 |
Advanced stage (III—IV) | 22 | 29 | 26 | 25 | ||