Experimental Hematology & Oncology

Overview

Experimental Hematology & Oncology publishes preclinical, basic, patient-oriented and translational research in all areas of hematology and oncology. The journal acts as an international platform for sharing laboratory findings and makes a deliberate effort to publish clinical trials with 'negative' results, as well as basic science studies with provocative findings. This peer-reviewed, open access journal offers impressive turnaround times with a time to first decision of less than 30 days.

Editors-in-Chief

Prof. Delong Liu MD, PhD
Prof. Kongming Wu MD, PhD

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Journal metrics

Journal Impact Factor: 17.5 (2025)

5-year Journal Impact Factor: 14.9 (2025)

Submission to first decision (median): 2 days

Downloads: 1.3M (2025)

Journal highlights

Article

Engineered circular RNA-based DLL3-targeted CAR-T therapy for small cell lung cancer

Purpose Circular RNA (circRNA) has emerged as a promising RNA therapeutic molecule due to its enhanced stability and prolonged protein expression compared to messenger RNA (mRNA). Using circRNA to construct transient…

Article

The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-…

Background Recent studies have shown that CD32/CD8a/CD28/CD3ζ chimeric receptor cells directly kill breast cancer cells, suggesting the existence of cell …

Article

Safety and efficacy of CD33-targeted CAR-NK cell therapy for relapsed/refractory AML: preclinical evaluation and phase I trial

Background Due to the lack of effective treatment options, the prognosis of patients with relapsed/refractory acute myeloid leukemia (R/R AML) remains poor. Although chimeric…

Calls for papers

Collection

Latest articles

Innovations and emerging trends in adoptive cell therapies for solid tumors: engineering strategies and clinical translation
Peng Huang
WenLin Wu
Xingchen Peng
Review Open access 22 October 2026 Article: 109
Oncogenic RAS as an adaptive signaling ecosystem: context-dependent vulnerabilities and resistance-informed therapeutic design
Amir Abbas Hamidi
Omeed Moaven
Mohammad Reza Abbaszadegan
Review Open access 22 October 2026 Article: 108
Cobimetinib impairs tumor survival and immune escape by altering my-CAFs in BRAFV600E-mutated anaplastic thyroid carcinoma
Mario Udinotti
Niclas Ramm
Barbara Seliger
Correspondence Open access 20 October 2026 Article: 107
Venetoclax-based combinations in high-risk myelodysplastic syndromes: highlights from ASH 2025 & EHA 2026
Ines Zugasti
Marina Cornejo
Marina Diaz-Beya
Correspondence Open access 16 October 2026 Article: 106
Part of 1 collection:

Latest updates from major conferences
Intratumoral microbiota in cancer immunotherapy: metabolic-epigenetic crosstalk and engineered bacterial therapeutics
Niying Zhao
Huan Zhang
Shuye Lin
Review Open access 16 October 2026 Article: 105

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Journal updates

Articles in Press
Springer Nature Editor of Distinction Awards 2026
CME Event

The Chinese American Hematologist and Oncologist Network (CAHON) are hosting their 13th Annual New York Oncology Forum on October 2-4, 2026. Scan the QR code for more details and to register.
Companion journal to Journal of Hematology & Oncology

Experimental Hematology & Oncology is a companion journal to Journal of Hematology & Oncology. Editor-in-Chief, Prof. Delong Liu explains more.

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Journal information

Electronic ISSN: 2162-3619
Abstracted and indexed in: BFI List

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Experimental Hematology & Oncology

Overview

Journal metrics

Journal highlights

Engineered circular RNA-based DLL3-targeted CAR-T therapy for small cell lung cancer

The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-…

Safety and efficacy of CD33-targeted CAR-NK cell therapy for relapsed/refractory AML: preclinical evaluation and phase I trial

Calls for papers

Tumor heterogeneity, metabolism and therapeutic Strategy

Oncobiome

Latest updates from major conferences

Latest articles

Innovations and emerging trends in adoptive cell therapies for solid tumors: engineering strategies and clinical translation

Oncogenic RAS as an adaptive signaling ecosystem: context-dependent vulnerabilities and resistance-informed therapeutic design

Cobimetinib impairs tumor survival and immune escape by altering my-CAFs in BRAFV600E-mutated anaplastic thyroid carcinoma

Venetoclax-based combinations in high-risk myelodysplastic syndromes: highlights from ASH 2025 & EHA 2026

Intratumoral microbiota in cancer immunotherapy: metabolic-epigenetic crosstalk and engineered bacterial therapeutics

Journal updates

Articles in Press

Springer Nature Editor of Distinction Awards 2026

CME Event

Companion journal to Journal of Hematology & Oncology

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